Kelechi Iheanacho hit a hat-trick as Leicester thrashed doomed Sheffield United 5-0 to move into second place in the Premier League, while Brighton improved their hopes of avoiding relegation with a vital win against Southampton on Sunday.
Leicester showed no mercy to bottom-of-the-table United in the visitors' first match since Chris Wilder's departure on Saturday.
Wilder, who led United from third-tier League One to the Premier League, left by mutual consent after several days of speculation about his future.
United, managed by interim boss Paul Heckingbottom, look destined for relegation after failing to build on last season's impressive first campaign back in the top flight.
The Blades, 14 points from safety with only nine games left, have lost six of their last seven league games.
Leicester pushed them closer to the Championship with their biggest win this season.
Nigerian striker Iheanacho opened the floodgates in the 38th minute at the King Power Stadium with a close-range finish from Jamie Vardy's pass after a flowing move.
Iheanacho's third goal in his last three games was followed by Ayoze Perez's fine strike from the edge of the area in the 64th minute.
Iheanacho scored again in the 69th minute from Vardy's cross and completed his treble with a 25-yard blast past Aaron Ramsdale.
Ethan Ampadu's own goal from Vardy's effort in the 80th minute sealed the rout for Brendan Rodgers' side, who moved above Manchester United and within 15 points of runaway leaders Manchester City.
